DOXYCYCLINE HYCLATE Tablets USP - 150 mg (count varies)

  • Doxycycline Hyclate Tablets are bioequivalent (similar) to the brand Acticlate┬«, another product used to treat severe acne.
  • Doxycycline Hyclate Tablets are an oral antibiotic and are effective against a variety of bacteria, including the bacteria that cause acne.
  • Doxycycline Hyclate Tablets may be prescribed as an adjunctive therapy, meaning that they may be used in combination with other treatment methods.
  • Scored tablets can be broken for a lower dosage.

Important Information


Doxycycline Hyclate Tablets USP 150 mg are indicated for adjunctive (combination) therapy in severe acne.

Important Safety Information

  • You should not take Doxycycline Hyclate Tablets if you have had an allergic or other reaction to doxycycline or any other tetracycline antibiotic. Avoid use of tetracyclines while also taking penicillin. Tetracycline-class drugs, like doxycycline hyclate tablets, can cause fetal harm when administered to a pregnant woman. Doxycycline Hyclate Tablets should be avoided if possible by nursing mothers and should not be used in children during tooth development (up to the age of 8 years). Concurrent use of tetracycline-class antibiotics with oral contraceptives may reduce their effectiveness.
  • Diarrhea has been reported with nearly all antibacterial agents including doxycycline and may range from mild diarrhea to fatal colitis.
  • Increased sensitivity to sunlight can occur with the use of tetracycline-class drugs. Doxycycline Hyclate Tablet patients should minimize or avoid excessive exposure to natural or artificial sunlight and consider using sunscreen or sunblock.
  • Overgrowth of non-susceptible organisms, including fungi, may occur. Doxycycline Hyclate Tablets should be discontinued if infection occurs and appropriate therapy instituted.
  • Intracranial Hypertension has been associated with the use of tetracyclines. Contact your doctor if you experience headaches, blurred vision, double-vision or vision loss.
  • Adverse reactions observed in patients receiving tetracyclines include anorexia, nausea, vomiting, diarrhea, rash, photosensitivity, urticaria, and hemolytic anemia.

For additional safety and other information, including Patient Information, please see Full Prescribing Information. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.